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W warunkach fizjologicznych GHK wystpuje w rwnowadze z miedzi osoczow, tworzc kompleks GHK-Cu, ktry traktuje si jako biologicznie aktywn form tego peptydu

Biochim Biophys Acta 1822:19311942

Long-term NMN administration promotes PINK1/Parkin-dependent mitophagy, decreases the accumulation of damaged mitochondria and reactive oxygen species, and improves follicular development and ovarian reserve [249]

Likewise, VEGF maintains the testicular blood vessels permeability 30 , which was matched with this work showing an elevation of VEGF in testicular tissues after treatment, other than its reduction in IR only, compared with sham rats

(Basel) 8 (10), 810